NSAID-Induced Gastric Damage in Rats
نویسندگان
چکیده
منابع مشابه
Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility.
This article reviews the pathogenic mechanism of non-steroidal anti-inflammatory drug (NSAID)-induced gastric damage, focusing on the relation between cyclooxygenase (COX) inhibition and various functional events. NSAIDs, such as indomethacin, at a dose that inhibits prostaglandin (PG) production, enhance gastric motility, resulting in an increase in mucosal permeability, neutrophil infiltratio...
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ژورنال
عنوان ژورنال: Canadian Journal of Gastroenterology
سال: 2001
ISSN: 0835-7900
DOI: 10.1155/2001/816962